Bina Prajapati

The paper identifies microtubule inhibitors as inducers of immunogenic cell death in MYChigh TNBC, linking MYC-dependent DAMP release to immune activation and tumor protection.

This study identifies enhanced mitochondrial respiration and glutamine-dependent TCA cycle as vulnerabilities in MYChigh breast cancer cells, showing synthetic lethality with complex I inhibitors.

The paper tracks transcription during erythroid differentiation and identifies NRF2's role in initiating an antioxidant program without oxidative stress.

The paper shows CCG-1423-derived compounds inhibit hsp gene transcription in fly and mammalian cells by reducing RNA polymerase II elongation and dampening heat shock responses.

This study identifies a direct interaction between actin and Cdk9 in P-TEFb, showing actin binds to actively elongating genes and inhibits polymerization during transcription.