Author

Manal Marzouk

Technion – Israel Institute of TechnologyORCID 0009-0008-7957-0060Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Deborah YablonskiiD· 2 shared Enas HallumiiD· 2 shared Naama Klopstock· 2 shared Dominic P. GoleciD· 1 shared Hirofumi ShibataiD· 1 shared J PerryiD· 1 shared Leslie J. BergiD· 1 shared Pamela L. SchwartzbergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Deborah YablonskiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 27, 2026

An ITK - SLP-76 Y173 Axis Regulates TCR Signal Persistence and Thymic Development

Manal Marzouk, J Perry, Enas Hallumi…·Deborah Yablonski

This study shows that the ITK-SLP-76 Y173 axis is essential for TCR signal persistence and thymic development, as its disruption reduces thymocyte cellularity and alters CD4/CD8 ratios.

DOI 10.64898/2026.10.22.760889

mouseexperimental assay

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ImmunologyEuropean Journal of ImmunologyPeer-reviewedFeb 1, 2025

Survival and Developmental Progression of Unselected Thymocytes in the Absence of the T Cell Adaptor Gads

Rose Shalah, Manal Marzouk, Enas Hallumi…·Deborah Yablonski

This study investigates the role of Gads in thymocyte development by ablating Gads and tracking thymocyte progression, finding that Gads is essential for TCR-driven checkpoints and death by neglect of unselected cells.

2 citations

mouseflow cytometry

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