Shoko Tamura

This study shows that restoring GLUT1 in both astrocytes and endothelial cells improves glucose homeostasis and cognitive function in GLUT1 deficiency syndrome.

The paper uses phase-targeting cryofixation to analyze sarcomere length dynamics in rat hearts, revealing contractile state-dependent spatial heterogeneity.

The paper introduces a technique to rapidly freeze biological systems during optical observation, enabling detailed time-specific analysis of cellular dynamics at high spatial resolution.

This study improves Raman microscopy's signal-to-noise ratio and resolution by imaging cryofixed biological specimens, enabling high-content chemical imaging under physiological conditions.