Author

Svenja Gramberg

Justus-Liebig-Universität GießenORCID 0009-0009-2108-4905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Simone HaeberleiniD· 3 shared Oliver PuckelwaldtiD· 2 shared Christos SamakovlisiD· 1 shared Claudia M. RohriD· 1 shared Daniel J. SpragueiD· 1 shared Emery W. SmithiD· 1 shared Evgeny G. ChulkoviD· 1 shared Janine KoepkeiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Simone HaeberleinORCID

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3 papers

Recent·Most cited

MicrobiologyNature Structural & Molecular BiologyPeer-reviewedMay 7, 2024

Target-based discovery of a broad spectrum flukicide

Daniel J. Sprague, Sang-Kyu Park, Svenja Gramberg…·Jonathan S. Marchant

The paper identifies a new flukicide, BZQ, effective against both Fasciola and Schistosoma species by targeting a conserved TRPMPZQ ion channel.

21 citationstop 1%

experimental assaydrug response / drug discovery

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 26, 2024

Single-cell transcriptomics identifies a p21-activated kinase important for survival of the zoonotic parasite Fasciola hepatica

Oliver Puckelwaldt, Svenja Gramberg, Sagar Ajmera…·Simone Haeberlein

The paper uses scRNA-seq to analyze Fasciola hepatica cells, identifies new cell types and gene expression patterns, and highlights PAK4's role in parasite survival.

2 citations

scRNA-seqstatistical model

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Molecular BiologybioRxivPreprintDec 11, 2023

Spatial transcriptomics of a parasitic flatworm provides a molecular map of vaccine candidates, drug targets and drug resistance genes

Svenja Gramberg, Oliver Puckelwaldt, Tobias Schmitt…·Simone Haeberlein

The paper presents the first spatial transcriptome of the liver fluke Fasciola hepatica, identifying gene expression profiles and markers for eight tissues, with focus on vaccine candidates, drug targets, and resistance genes.

3 citations

spatial transcriptomicsexperimental assay

𝕏 PostBluesky