Author

Mia P. Sams

Western UniversityORCID 0009-0009-4677-0442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Rodney P. DeKoteriD· 2 shared Allanna C. E. MacKenzie· 1 shared Bruno Rodrigues de Oliveira· 1 shared Carolina R. Batista· 1 shared Chanpreet K. Riarh· 1 shared Heidi RysaniD· 1 shared James Iansavitchous· 1 shared Jane H.-C. Lin· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Rodney P. DeKoterORCID

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2 papers

Recent·Most cited

ImmunologyMolecular ImmunologyPeer-reviewedSep 26, 2024

Negative regulation of Activation-Induced Cytidine Deaminase gene transcription in developing B cells by a PU.1-interacting intronic region

Allanna C. E. MacKenzie, Mia P. Sams, Jane H.-C. Lin…·Rodney P. DeKoter

The paper identifies a PU.1-interacting intronic region that negatively regulates Aicda transcription in developing B cells.

DOI 10.1016/j.molimm.2024.09.010

mouseexperimental assay

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Cancer BiologyJournal of Pharmacology and Experimental TherapeuticsPeer-reviewedFeb 9, 2024

N-Acetylcysteine alters disease progression and increases Janus Kinase mutation frequency in a mouse model of precursor B cell acute lymphoblastic leukemia

Mia P. Sams, James Iansavitchous, Madeline Astridge…·Rodney P. DeKoter

This study shows that N-acetylcysteine (NAC) alters disease progression in a mouse model of B-ALL by increasing Jak3 R653H mutation frequency.

2 citations

mousebulk RNA-seq

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