Author

Sofia Rodríguez-Rangel

Universidad de GuadalajaraORCID 0009-0009-6807-7059Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Jorge E. Sánchez‐RodrígueziD· 2 shared Pedro BrugarolasiD· 2 shared Yang SuniD· 2 shared Brenda Mata OrtegaiD· 1 shared Lauren L. ZhangiD· 1 shared Oscar Gutiérrez Coronado· 1 shared Saadi El-SaadiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

Jorge E. Sánchez‐RodríguezORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BiochemistryNeuropharmacologyPeer-reviewedOct 7, 2026

4-methyl-3-aminopyridine: A novel active blocker of voltage-gated potassium ion channels in the central nervous system.

Sofia Rodríguez-Rangel, Oscar Gutiérrez Coronado, Brenda Mata Ortega…·Jorge E. Sánchez‐Rodríguez

This study characterizes 4-methyl-3-aminopyridine as a potent KV channel blocker with improved pharmacological properties compared to 4-aminopyridine.

DOI 10.1016/j.neuropharm.2026.111216

mouseelectrophysiology

𝕏 PostBluesky

Pharmacology & ToxicologyScientific ReportsPeer-reviewedMay 15, 2024

Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine

Yang Sun, Sofia Rodríguez-Rangel, Lauren L. Zhang…·Pedro Brugarolas

This paper characterizes 5Me3F4AP, a novel K+ channel blocker with improved physicochemical properties and stability compared to existing PET tracers for demyelinated lesion imaging.

3 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky