Mirentxu Santos

This paper develops CMD-coated magnetic nanoparticles for delivering CRISPR RNPs, demonstrating efficient genome editing in cell lines and a skin disorder model.

This paper introduces a non-viral CRISPR/Cas9 method using cationic polymers to generate mouse lung cancer models by inactivating tumor suppressor genes, enabling rapid and flexible hypothesis testing.

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.