electrophysiology

The paper shows that homogeneous excitable cells and tissues generate no extracellular potentials, even with action potentials, and explains when EPs emerge.

Adding distributed muscle mass to 1D Hill-type models alters predicted human leg-muscle forces by under 1% at natural size; differences grow with scale and cadence.

This study identifies a pressure-sensitive regulatory mechanism of L-type Ca2+ channels that influences cerebral blood flow control and cognitive function.

This paper develops a biological brain-based gas sensor using locust olfaction to detect and classify multiple PFAS with high accuracy.

The paper compares two custom-built electrodes to a discontinued commercial electrode for neuromuscular stimulation in mice, finding no significant differences in torque output.

This study shows that cardiac activity slows when auditory deviations are synchronized with heartbeats, regardless of their type or predictability.

This study shows that interpersonal breathing synchronization during social interaction leads to reduced intrapersonal cardiorespiratory coupling, suggesting a trade-off between self-other and self coupling.

Senolytic treatment with dasatinib plus quercetin after carotid artery occlusion reduces infarct size and improves outcomes in aged rodents with ischemic stroke.

This study shows that temporal interference stimulation enhances neural progenitor cell maturation in vitro and promotes hippocampal neurogenesis in a mouse Alzheimer's model.

Ryanozole, a RyR2-selective stabilizer, prevents stress-induced arrhythmias without impairing cardiac function in CPVT mouse models.

The paper introduces the MMH dataset, which includes kinematic, force, and sEMG data from load lifting and lowering tasks to support musculoskeletal modeling and ergonomic risk assessment.

The paper investigates the effect of the GABAA receptor α4 subunit variant Ile114Asn on membrane expression when combined with β3 and δ subunits, finding reduced maximal GABA-elicited currents.

This study uses multiverse analysis to evaluate the consistency of gastric-brain coupling measurements across different analytic pipelines in EEG-EGG data from healthy humans.

The paper presents a multimodal dataset of EEG, eye-tracking, and physiological signals during smartphone interactions and relaxation, enabling analysis of neural and autonomic responses.

This study identifies endothelin signaling via EDNRB as a regulator of glioma cell proliferation and proneural-to-mesenchymal transition, with distinct receptor expression and functional roles in different tumor subtypes.

This study shows PRKAG2 variants cause cardiac hypertrophy and electrical changes in zebrafish, independent of glycogen storage, through AMPKγ2-myosin interactions.

This paper introduces a QRS detector using MLP-assisted peak scoring and combinatorial optimization, achieving high sensitivity and PPV in noisy signals.

This study identifies an extracellular K+ binding site in Cys-loop receptors that modulates pore conformations and Cl- conductance, with similar mechanisms observed in a human glycine receptor variant.

This study evaluates how different QRS detection algorithms affect HRV metrics across various recording setups and conditions, finding significant variability in performance and recommending context-specific algorithm selection.

This paper evaluates a wearable dual-modality device combining IPG and PPG, showing IPG's superior sensitivity to arterial recovery and dynamic changes during napping.

The paper measures PMF dynamics in E. coli under hyperosmotic stress using the flagellar motor as a voltmeter, finding rapid and reversible PMF loss.

This study evaluates the clinical value of conductive cardiac patches by testing different conductivities and shows that higher conductivity reduces arrhythmia risks in post-MI hearts.

This study shows that reducing STIM1 in cardiomyocytes causes mitochondrial fragmentation and metabolic changes, leading to electrical instability and worsened heart function after a heart attack.

This paper introduces E-cardiac, a biosensor that monitors oxidative stress in beating hearts with mechanical adaptation, distinguishing ischemia-reperfusion injury severity and detecting the ECG blind window.

This paper presents a simplified Langendorff-based method for isolating adult mouse ventricular myocytes using syringe pump-driven perfusion, improving reproducibility and accessibility.

This study shows NAADP reverses Lsm12 inhibition of PI(3,5)P2-dependent TPC activation, enabling Ca2+ release from acidic organelles.

This paper quantifies cerebellar signal detectability in MEG and EEG for epilepsy using anatomically informed source modeling, finding that depth and geometry, not proximity, primarily affect signal-to-noise ratio.

This paper uses multifractal analysis of electrograms to distinguish atrial fibrillation phenotypes, predict drug response, and identify imminent termination.

This paper introduces a two-stage digital twin brain model constrained by EEG and fMRI data, showing it captures multi-scale brain dynamics in healthy and Alzheimer's disease cohorts.