electrophysiology

This study investigates neural adaptations in muscle strength and force steadiness in untrained limbs after unilateral training, finding reduced synaptic input variability and increased neural drive in trained and contralateral limbs.

This study constructs a dmPFC circuit model to explore how neural bistability influences social dominance behaviors and reveals the trade-offs between perseverance and flexibility in competitive contexts.

The paper shows that clustering of voltage-gated sodium channels affects their biophysics, leading to different pharmacological responses and potential therapeutic implications.

This study investigates how APOE genotype affects sleep architecture, finding that APOE4 homozygotes have higher arousal thresholds and reduced sleep spindle activity.

This paper develops micro-invasive probes for dual chemical and electrical neural activity recording in nonhuman primates, demonstrating long-term functionality over one year.

The paper examines infra-slow EEG rhythms and bodily signals during social interaction, finding that mutual recognition is associated with enhanced inter-participant alignment in 0.1 Hz EEG power and other physiological measures.

This study identifies IQM-22110 as a selective KV4.3/KChIP3 modulator, showing it binds specifically to KV4.3/KChIP3 and not KV4.3/KChIP2 or KV4.3 alone.

This study links TRPM8 protein dynamics to ligand structure and cellular function using NMR, cheminformatics, and electrophysiology.

This study shows that preterm growth-restricted lambs have altered cardiovascular responses to perinatal asphyxia, including impaired vascular contractility and dysregulated adrenergic receptor function.

The paper develops and validates a multi-muscle fatigue model using EMG parameters and muscle ratios to predict fatigue in operational tasks.

This study investigates how pulsed transcranial photobiomodulation (tPBM) parameters affect EEG oscillations, finding parameter-dependent changes that contradict entrainment predictions and highlighting sex as a key biological modulator.

This study uses hiPSC-derived atrial cardiomyocytes and fibroblasts to model atrial fibrillation through intermittent tachypacing, showing increased AP frequency and fibrosis markers.

The paper shows that saccades and fixations are coordinated with the cardiac cycle, with saccades occurring during systole and fixations during diastole.

The paper proposes a mechanism by which extracellular calcium regulates the resting state of outer-hair-cell bundles through changes in stereocilium height and builds a model to support this hypothesis.

This study identifies how TC-2559, a super-agonist, modulates the high sensitivity nicotinic acetylcholine receptor through both orthosteric and allosteric binding sites, enhancing channel opening.

The paper investigates how glioma infiltration affects the aperiodic slope of neural dynamics, finding it correlates with excitation dominance and semantic naming impairments.

This paper improves multimodal EEG-fTCD brain-computer interfaces using FBCSP and envelope features, achieving high classification accuracies for motor imagery and mental rotation tasks.

This study identifies two existing drugs that reduce KCNT1 channel activity and seizure activity in Drosophila models, suggesting potential new treatments for KCNT1-epilepsy.

This paper develops a calibration-free P300 BCI system with real-time performance comparable to offline benchmarks, using pre-trained models and a small electrode setup.

The paper validates ephaptic coupling in human neuronal circuits using a reproducible in vitro method, showing reduced action potential velocity and increased synchronization.

This study investigates gastric slow-wave morphology as a biomarker for disease, finding differences between healthy controls and patients with chronic unexplained nausea and vomiting.

This study uses dysfunctional electrical stimulation to perturb treadmill walking and identifies conditions that reduce postural stability.

This study investigates how thermal acclimation affects spreading depolarization in Drosophila melanogaster, showing enhanced resistance to cold- and anoxic SD and interactive effects on TPP and SD propagation.

This study shows that repeated levodopa treatment in Parkinsonian mice leads to striatal adaptations, specifically enhanced glutamatergic synapses on D1-MSNs and reduced D2R sensitivity, which contribute to worsening dyskinesia.

This study shows that oxytocin receptor absence in prairie voles impairs peer relationship formation, stability, and reward, with reduced oxytocin release in the nucleus accumbens.

This study identifies the C-terminal domain as the temperature sensor in TREK channels and shows that microtubule interaction and PKA phosphorylation regulate their thermosensitivity.

NIRSTORM extends Brainstorm for fNIRS analysis, offering 3D hemodynamic reconstructions and optimal probe design within a multimodal framework.

The paper develops CoVET, a technique correlating electrophysiological properties with cryo-ET to analyze neuronal molecular structures and translational landscapes.

The paper provides functional evidence supporting a model of PC1/PC2 heteromer ion channel function through structure-guided mutagenesis and electrophysiological analysis.

This study compares frequency-dependent and capacitive tissue properties in spinal cord stimulation models to assess their impact on electric fields and heating, finding that quasi-static approximation remains valid under certain conditions.