flow cytometry

This study shows that influenza virus infection causes reduced immune cell counts and impaired differentiation in the thymus and bone marrow, linked to systemic inflammation and oxidative stress.

The paper develops fluorescence-barcoded cell lines expressing membrane-anchored influenza neuraminidases to study antibody responses and vaccine efficacy.

The paper develops a high-throughput platform to profile antigen-specific CD4+ T cells at single-cell resolution, identifying immunogenic features and functional heterogeneity in viral and cancer contexts.

This study shows that AAT-overexpressing MSCs reverse T1D in NOD mice by enhancing Treg function and inducing CD8+ T cell exhaustion.

This study identifies pathogen-specific neutrophil surface protein phenotypes in bacterial pneumonia, revealing tissue- and infection-type dependent immune responses.

This study analyzes the immune response to Bexsero vaccine in mice, showing robust humoral and cellular responses but inconsistent protection against Neisseria gonorrhoeae.

The paper optimizes a LIVE/DEAD assay using flow cytometry to quantify post-stress and antifungal-treatment survival in yeasts, identifying an intermediate cell population with enhanced SYTO 9 uptake.

This study investigates IgG glycosylation patterns in HFRS patients, finding increased fucosylated IgG and decreased bisecting N-acetylglucosamine during recovery, with correlations between glycosylation and B cell subsets.

This study investigates cross-species immune responses induced by meningococcal OMV vaccines and their association with protection against N. gonorrhoeae.

This study quantifies membrane vesicles in freshwater ecosystems using flow cytometry and interferometric microscopy, finding agreement in nanoparticle abundance and suggesting associations with virus particles or dense compounds.

The paper identifies polysialylated NCAM as a marker distinguishing differentiated from proliferating myoblasts before fusion.

This study shows FLASH radiotherapy preserves lymphocytes and increases immune cell infiltration in tumors, potentially improving antitumor immune responses.

This study shows that PLCγ2 controls neutrophil sensitivity via calcium oscillations and regulates chemoattractant concentration range for chemotaxis.

This study introduces a biopsy technique combined with cytometric fingerprinting to analyze spatial heterogeneity in bacterial colonies, revealing distinct physiological states across different locations.

The paper investigates how vaccine antigen delivery and adjuvant selection affect the priming of rare HIV broadly neutralizing antibody-precursor B cells in non-human primates, finding that specific dosing and adjuvant combinations enhance their detection in germinal centers.

The paper identifies a rare subset of CD4 and CD8 double positive T cells that form clusters with circulating tumor cells, promoting cancer metastasis through immune suppression and integrin-mediated interactions.

This study evaluates the immunomodulatory effects of ivermectin in mild COVID-19 patients and finds no significant immune response changes, consistent with clinical trial results.

This study shows TNBC cells acquire CD45 proteins and T cell genomic DNA through trogocytosis, altering their gene expression and expressing CD45 on and inside the cells.

This study characterizes CAR+ T-cell subsets and immune system dynamics in pediatric BCP-ALL patients treated with tisagenlecleucel, finding correlations between immune cell changes and cytokine release syndrome.

This study examines immune responses in craft and manual workers after a BNT162b2 booster, showing enhanced Th1 and cytotoxic T cell responses, and durable humoral immunity, with prior infection boosting B cell counts.

This study investigates how bacterial vaginosis alters cervicovaginal immunity, identifying immune cell changes that may contribute to increased HIV susceptibility.

This study identifies antigen-specific CD8+ T-cell responses linked to disease severity in SARS-CoV-2 infection, showing functional impairment and recognition bias.

This paper shows that serine proteases from diarrheagenic bacteria cleave CD45 and induce T-cell apoptosis, mimicking IL-2 deprivation and contributing to bacterial virulence.

The paper finds that ApoE ε4-dependent changes in CXCR3+CD127+ CD4+ T cells in peripheral blood correlate with elevated neurofilament light chain in Alzheimer's disease.

This paper characterizes lysosomal storage disease using imaging and cytometry to assess lipid homeostasis in patient cells and validates findings in alternative models.

The paper identifies an early expansion of adaptive NK cells during acute HIV-1 infection that correlates with long-term viral control.