metagenomics

This study shows heat-killed Latilactobacillus sakei D279 reduces LPS-induced intestinal inflammation and barrier disruption in mice, macrophages, and epithelial cells.

This study investigates the molecular and phytochemical differences between two types of Tibetan medicine 'Talegabao' and 'Talenabao' from Rhododendron species on the Qinghai-Xizang Plateau, identifying DNA barcode and chemical markers for their discrimination.

This study tracks within-host evolution of an avirulent Salmonella vaccine strain and finds that regulatory tuning of the BarA/SirA system reduces SPI-1ON cells without losing SPI-1 function.

The paper shows that impaired gut microbiota fermentation of inulin leads to intestinal inflammation in mice, highlighting the importance of microbial metabolism in fiber tolerance.

This study demonstrates the transferability of homoserine lactone sensors between Bacillales bacteria, enabling programmable interphyla communication between Gram-negative and Gram-positive species.

This paper introduces GeneEmbedLLM, a framework using large language models to generate gene embeddings from multi-source textual annotations, achieving competitive performance in various downstream tasks.

AOPTK automates toxicological literature analysis using AI, achieving high accuracy in identifying chemical-biological effect relationships.

This study investigates how varying iron levels in diets affect the nutritional profile and microbiome of house crickets, finding that high iron increases their iron content without altering microbial diversity.

CauloBrowser 2.0 updates the systems-biology database for Caulobacter crescentus with AI-powered tools for querying and visualizing experimental data.

This study shows that timing of TGF-β blockade and material context affect matrix retention in bioprinted keratoconus stroma, with optimal regimens improving collagen retention and reducing contractile gene expression.

This study develops a synthetic cleavage module that selectively degrades pathogenic r(CUG) repeats in cells, reducing DM1-associated pathology without DNA damage.

The paper evaluates contrastive learning on VOC-OR binding datasets, showing improved generalization and reduced performance inflation from identity leakage.

This study introduces TISCA2 and IncepTIS to map and predict stress-responsive translation initiation sites, revealing tissue-specific patterns and enabling engineered mRNA 5' leaders.

This study evaluates genetic variation in maize's response to chilling stress and recovery, identifying heritable traits linked to cold resilience.

This study evaluates AlphaFold 3's accuracy and reliability in predicting RNA structures and protein-RNA interfaces, finding that confidence scores do not always correlate with correct predictions.

The paper identifies germ granule-like amyloid/RNA condensates in rat epididymal spermatozoa that exhibit prion-like propagation activity, suggesting a non-Mendelian mechanism for transmitting environmental information to offspring.

The paper shows that CO2-concentrating nanoparticles modify photosynthesis and cell wall structure in Arabidopsis cells over time.

This study identifies RBM3 as a host factor that promotes PEDV infection by stabilizing viral RNA and upregulating the entry factor HSPA5.

This study investigates microbial responses to oil spills in Arctic conditions by simulating oil degradation and marine oil snow formation in microcosms at 4°C.

GraphExperiment provides an R/Bioconductor package to store and manipulate high-dimensional quantitative data alongside associated networks in a unified framework.

The paper investigates how a bacterial chaperone-usher pathway enables interkingdom protection of a fungus from antimicrobial compounds.

This study shows that ESX-5 deletions in Mtb reduce cytokine secretion in macrophages via a post-transcriptional mechanism and alter heavy metal response genes.

This study investigates the role of Casd1 in sialic acid O-acetylation of intestinal mucus and its impact on tissue damage susceptibility in mice.

This study uses multi-omics to uncover Gardnerella genomic features linked to biofilm formation and interspecies interactions in the vaginal microbiome, identifying potential therapeutic targets for bacterial vaginosis.

This study shows AP2-L is essential for Plasmodium liver-stage development by regulating PVM formation and host-cell interactions.

The paper introduces FennoTraits, a dataset of plant functional traits and community composition from northern European flora, highlighting trait patterns and species distribution across seven study areas.

This study shows that Pantoea ananatis triggers systemic resistance in Arabidopsis through root sensing via the LORE receptor kinase, using HAAs and 3-OH-C10 as MAMPs.

This study investigates cognitive symptoms in post-COVID-19 condition with fatigue, finding subtle neurobiological changes not captured by standard assessments.

This study identifies self-cleaving ribozymes in RNA viruses, showing their role in translation initiation across fungi and plants.