development & morphogenesis

Adaptive immunity is dispensable for salamander appendage regeneration

Rag1-knockout newts lacking adaptive immunity regenerate larval limbs, tails and adult limbs without overt gross differences from controls; newt blastema tolerates allografts, and axolotl regenerating limbs show immunosuppressive transcriptional shifts.

Iron-dependent reprogramming of damage-associated peptide receptor signaling coordinates immunity and phosphate stress adaptation

Phosphate starvation in Arabidopsis potentiates Pep-PEPR signaling, but not flagellin or chitin responses, via LPR1/LPR2 iron-redox, RBOHD/RBOHF and WRKY33; basal PEPR activity also supports phosphate-starvation responses.

Genetic canalization of nutrient resorption: evidence from a widespread grass under effective salt stress

In 110 common-garden Phragmites australis genotypes, effective salt stress left N, P and K resorption efficiency largely unchanged; efficiency instead tracked phylogeographic lineage, ecotype and latitude.

Impact of Reduced Chlorophyll Levels in Leaves on Soybean Yield, Seed Composition, Pod/Seed Photosynthesis, and Chlorophyll Levels in Pod and Seed Tissues

Among 25 low-chlorophyll soybean mutants, a Lincoln mutant raised seed protein without yield loss, while Clark-derived Y11/y11 lowered seed oil alongside reduced pod gross photosynthesis.

Mechanically Compliant, Precision-Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

Brain-stiffness-matched pHEMA/GMA hydrogel scaffolds with 40 µm interconnected pores reduced astrocyte encapsulation and iNOS+ macrophage fraction versus stiff solid rods after 4 weeks in rat brain.

Nuclear size and physical properties of the nucleoplasm are determined by colloid osmotic pressure at the nuclear envelope

Overexpressing mCherry-GST targeted to the nucleus or cytoplasm in fission yeast shifts the nuclear-to-cell volume ratio as a parameter-free colloid osmotic model predicts, retuning nucleoplasm diffusivity, condensates and heterochromatin.

Galvanin (TMEM154) is an electric-field sensor for directed cell migration

A CRISPRi migration screen in neutrophil-like HL-60 cells identified Galvanin (TMEM154), a single-pass membrane protein whose negatively charged ectodomain electrophoreses anodally to steer cathodal electrotaxis.

From lab to ocean: bridging swimming energetics and wild movements to understand red drum (Sciaenops ocellatus) behavior in a tidal estuary

Red drum lowered oxygen consumption behind mangrove- and oyster-mimicking bluff bodies at flows to 100 cm/s, yet telemetered fish were detected mostly in low-velocity nearshore habitat.

A cross-center comparison of the relationship between matriline fragmentation, grooming cohesion, and agonistic behavior in captive rhesus macaque (Macaca mulatta) social groups

Across 105 rhesus macaque matrilines at two primate centers, family grooming cohesion drops below a mean kinship threshold of 0.16, while lower kinship continuously increases severe within-family aggression.

Peaceful Queen Succession in the Naked Mole Rat

Relocating a captive naked mole rat colony paused the queen's breeding; two daughters then sequentially became breeders without aggression, ending in peaceful succession.

INDETERMINATE DOMAIN-DELLA protein interactions orchestrate gibberellin-mediated cell elongation in wheat and barley

Wheat IDD5 and barley SDW3, orthologous zinc-finger transcription factors, bind DELLA proteins and promote gibberellin (GA)-driven elongation; their loss-of-function mutants are GA-insensitive semi-dwarfs resembling Rht-D1b.

Beyond species means - the intraspecific contribution to global wood density variation

Across 109,626 wood density records from 16,829 plant species (GWDD v.2), intraspecific variation explains 15% of global variance, tracks interspecific environmental gradients at 20-30% magnitude, and limits single-plant predictability.

Age-associated increased stiffness of the ovarian microenvironment impairs follicle development and oocyte quality and rapidly alters follicle gene expression

Hydrogels matching aged mouse ovary stiffness (5.85 kPa vs 0.84 kPa) cut follicle survival to 6.66% to 30%, reduce estradiol up to 533-fold, and alter 135 genes within 6 hours.

IGP receptors act as redox sensors to mediate broad-spectrum disease resistance induced by cellooligomers

Plant LRR-Malectin receptor kinase IGP1 binds cellooligomers via its leucine-rich repeat domain while a conserved cysteine pair in its malectin domain senses hydrogen peroxide to attenuate immune signaling.

Cerebral Organoids with Integrated Endothelial Networks Emulate the Neurovascular Unit and Mitigate Core Necrosis

Embedding day-8 cerebral organoids in Geltrex loaded with human brain microvascular endothelial cells, plus VEGF-supplemented mixed media, yields integrated endothelial networks and almost three-fold less apoptosis.

The role of ERFVIIs as oxygen-sensing transducers in the evolution of land plant response to hypoxia

Hypoxic induction of glycolysis and fermentation genes spans the land plant divisions tested, while oxygen-regulated group VII Ethylene Response Factors (ERFVIIs) carrying Cys2 occur only in vascular plants.

Impact of soil moisture on microbial diversity and their enzyme activity on agricultural soil

Two months of induced summer drought in four Polish agricultural soils lowered bacterial counts, dehydrogenase activity and BIOLOG carbon-substrate use, each tracking declining soil moisture.

Hybridogenetic reproduction of Pelophylax water frogs from different R-E hemiclonal population systems from Eastern Ukraine: selective mortality, clonal and ploidy diversity

Siverskyi Donets water frog systems lacking P. lessonae split into diploid-only and diploid-plus-triploid hybrid types, with clonal, low-diversity L-genomes and steep tadpole-to-adult loss of P. ridibundus.

N,N-dimethylacetamide blocks inflammation-induced preterm birth and remediates maternal systemic immune responses

A two-dose DMA regimen on gestational day 15 prevented LPS-induced preterm birth in CD-1 mice, reversed cytokine surges within days, and spared term parturition.

Genetic requirements for cell division in a genomically minimal cell

Seven genes, including ftsZ, sepF and five of unknown function, are jointly required to restore near-normal morphology and division in the minimal cell JCVI-syn3.0.

Reversed graph embedding resolves complex single-cell developmental trajectories

Monocle 2 learns branched single-cell trajectories without supervision via reversed graph embedding, revealing a non-fusing myoblast outcome and knockout myeloid cells diverted onto opposite fate branches.