Gut microbiota and health

The paper shows that two diets reduce CRC development in APCMin/+Msh2-/- mice by inducing ER stress and enhancing barrier function through upregulation of Muc-2 and heat shock proteins.

This study shows that dihydromyricetin improves insulin resistance by enhancing GLP-1 secretion through the gut microbiota-CDCA pathway in HFD-induced mice.

The paper identifies shared metabolic trends between degraded soils and T2D gut microbiomes, showing increased sugar metabolism and reduced lignin and branched-chain fatty acid metabolism.

This study shows how initial population size and resource competition shape gut microbial community coalescence, with dose-dependent effects persisting even after many generations.

FAVA quantifies compositional variability across multiple microbiome samples using a normalized index, enabling comparison of taxonomic or functional relative abundances across different conditions and sample numbers.

This study investigates gut microbiome and metabolome changes in diabetic mice co-infected with tuberculosis, identifying dysbiosis and metabolic alterations associated with comorbidity.

This study identifies innate immune signaling and CD11b+CD11c+CD103+ cell migration to the brain as mechanisms linking microbial colonization to behavioral changes in mice.

This study shows that rice particle size affects gut microbiota functionality and microbial metabolite production through changes in surface area and fiber content.

The paper develops a novel measure, CheSL Shannon diversity, to quantify carbohydrate complexity's effects on microbial diversity, interactions, and function in human fecal samples.

The paper introduces mTMAT, a statistical method for analyzing longitudinal microbiome data to detect associations with host diseases while being robust to compositional bias.

This study shows that sulfide is essential for gut microbial and immune homeostasis, with its depletion causing immune dysfunction and impaired vaccine response.

The paper links gut microbiome functional gene pathways to cognitive performance in older adults with Alzheimer's disease, identifying specific metabolic pathways associated with cognitive decline.

The paper models how microbial intake affects gut microbiome diversity and identifies an optimal feeding strategy to maximize time-averaged Shannon diversity.

The paper designs human gut microbiome communities using machine learning to optimize responses to dietary fibers, identifying beneficial fiber-species combinations that enhance butyrogenic properties.

This paper introduces LUPINE, a method for inferring microbial networks in longitudinal studies, and validates it using simulated data and case studies.

This study shows that gut microbiota and their metabolites contribute to OSA-induced atherosclerosis, particularly in the aorta, through specific bacterial imbalances and bile acid dysregulation.

This study shows that Aspergillus fumigatus infection in immunosuppressed mice disrupts lung microbiome balance, increasing anaerobic bacteria like Ligilactobacillus murinus, which can be internalized by epithelial cells.

The paper identifies Health-Associated Core Keystones (HACKs) in the human gut microbiome using large-scale data, showing their association with health and resilience, and their potential in therapeutic applications.

The paper shows that strain sharing in microbiomes can reflect both transmission and environmental factors, emphasizing the need for careful study design.

This study isolates and characterizes a novel Clostridium species, C. filamentum ETTB, which modulates the TLR5 pathway in host cells and has distinct genomic features compared to related species.

This study shows that sex and mitochondrial-haplotype influence age-related changes in gut microbiome composition and metabolites in rats.

The paper introduces SWipe, a low-cost stool collection method for gut metabolomics that enables accurate, reproducible, and convenient sample collection for large-scale studies.

This study predicts ecological relationships between human gut bacteria using time-series data from US travelers in Bangladesh, identifying both cooperative and competitive interactions with metabolic and genomic support.

This study investigates how hyperglycemia worsens gut barrier disruption and liver immune dysfunction after myocardial infarction, leading to increased microbial dissemination and systemic inflammation.

This study examines gut microbiota repopulation and dietary intake patterns after a colonoscopy, showing increased energy intake and changes in fiber consumption correlate with microbial diversity shifts.

The paper uses a knowledge graph to hypothesize mechanistic links between microbes and disease by analyzing relationships between microbes, genes, and metabolites.

The paper investigates how Blastocystis subtypes in non-human primates influence gut microbiome composition and shows that specific microbial features can predict Blastocystis load.

This study shows ketogenic diets restore gut microbiome alterations in Alzheimer's mice by reducing Bifidobacterium and increasing short-chain fatty acid-producing bacteria.

This study shows that the 16p11.2 microdeletion worsens neurodevelopmental issues caused by early-life antibiotic exposure, affecting gut microbiota, hippocampal development, and behavior.

This study shows that gut microbiome flagellin affects vaccine reactogenicity and can be influenced by diet.