Stress Responses and Cortisol

This study shows that early life stress causes sex-specific behavioral changes and alters locus coeruleus neuron excitability in mice, with female mice showing more pronounced effects.

This study investigates how metyrapone, an 11β-hydroxylase inhibitor, affects offspring behavior and corticosterone levels in a rodent model of maternal immune activation, revealing sex-specific outcomes.

The paper characterizes CRF synaptic contacts on DA and non-DA neurons in macaque PBP and A8 regions, finding inhibitory CRF synapses predominantly on TH-negative dendrites, with similar patterns in males and females.

This study shows that genomic glucocorticoid receptor activity in the basolateral amygdala is essential for delayed anxiety and dendritic spine plasticity after acute stress in rats.

The paper investigates whether elevated H1x protein levels in the ventral hippocampus cause stress-related behavioral adaptations, finding no significant behavioral effects from H1x overexpression.

The paper shows that pubertal androgen exposure programs adult behavioral responses to social defeat stress, with effects mediated by the bed nucleus of the stria terminalis.

This study shows that repeated social defeat stress in male prairie voles leads to depression-like behaviors including reduced sociability, anhedonia, and spatial memory impairment.

This study examines how chronic alcohol consumption affects hypothalamic CRH neurons in male and female mice during withdrawal, revealing sex-specific changes in stress responses and neuronal excitability.

The paper examines how stress-induced brain responses relate to BMI in women, finding that specific brain regions predict BMI and that endocrine factors, not inflammation, are linked to these changes.

This study examines correlations between biomarkers and stress by analyzing hormonal and cardiovascular data from healthy participants during a stress-induced task.

This study shows that a socio-affective mental training module increases hippocampal subfield volume and functional connectivity, correlating with reduced cortisol levels in healthy adults.

The paper shows that early-life stress sensitizes neurons in the nucleus accumbens to reactivate during adult stress, contributing to stress hypersensitivity.

This study maps CRF, its receptors, and binding protein mRNA expression in chicken telencephalon during development using in situ hybridization, revealing age-related changes in stress-related gene expression patterns.

This study shows that Krtcap3 knock-out rats exhibit increased adiposity and anxiety under chronic stress, with altered corticosterone responses and Nr3c1 expression.

This study investigates the link between social isolation stress and somatic mutations in the hippocampus using mouse models and demographic data from quarantined individuals.

This study shows that early-life stress in male mice reduces response bias for highly rewarded stimuli in a translational reward task, suggesting potential parallels with human depression.

This study examines how social instability stress during adolescence affects prefrontal cortex proteomics in rats, revealing sex- and age-dependent molecular changes.

This study examines how social dominance rank in mice affects PACAP expression, corticosterone levels, and behavior, finding higher PACAP in subordinates and lower corticosterone in subordinates.

The paper identifies indirect molecular links between early life adversity and adult social anxiety disorder through immune-related signal transduction pathways using transcriptome analysis.

The paper identifies persistent post-stress activity of paraventricular thalamic neurons as critical for stress-induced maladaptive behavior and shows that inhibiting this activity can alleviate symptoms.

This study shows that chronic paternal stress in mice leads to sex-specific effects on offspring behavior, partially mediated through changes in maternal care and investment.

The paper links changes in large-scale neural networks during lab stress to real-life affective reactivity.

This study investigates how chronic stress affects neural processing of affective stimuli in the vmPFC of male and female rats, revealing sex-dependent and context-specific changes.

The study identifies brain regions whose activation during initial social stress predicts future resilience or susceptibility in mice using the CSDS model.

This paper investigates whether riluzole can reverse stress-induced delayed effects on the amygdala in rats, finding it reduces anxiety-like behavior and synaptic changes.

This study shows that blocking estrogen receptor beta in the central amygdala prevents stress-induced anxiety and depressive behaviors in female rats exposed to repeated social stress.

This study investigates how positive coping in children affects emotional wellness through neuroendocrine mechanisms, showing that cortisol awakening response mediates the relationship between coping and hippocampal-neocortical connectivity.

This study identifies dscaml1 as critical for CRH neuron development and stress axis function in zebrafish, showing its role in regulating cell number and stress hormone levels.

This study investigates the lifelong molecular effects of high glucocorticoid exposure during development using a zebrafish model, identifying GC-primed genes and epigenetic changes linked to psychiatric disorder risk factors.

This study examines how footshock stress affects social behavior and neuronal activation in male and female mice, finding sex-dependent changes in defensive behaviors and cFos expression.