Stress Responses and Cortisol

This study shows that fentanyl interacts with the HPA axis over different timescales, with adrenal remodeling encoding stress history to influence fentanyl-seeking behavior.

This study examines how early dopamine elevation interacts with maternal separation in mice, showing sex-specific behavioral and hippocampal volume changes.

This study shows that prenatal stress leads to different brain aging patterns in male and female mice, affecting behavior and cognition through sex-specific mechanisms involving insulin resistance and hormonal changes.

This study investigates the effects of 3-aminobenzamide (3-AB), a PARP inhibitor, on chronic stress-induced behavioral, cardiovascular, and neuroinflammatory changes in rats, finding protective effects against behavioral deficits and neuroinflammation.

This study shows that early-life adversity increases IL-17A levels in female mice blood, linking it to autoimmune disease risk, while also affecting other proteins in both sexes.

This study investigates sex-specific stress responses to acute and chronic social defeat stress, finding differences in behavioral outcomes between males and females.

This meta-analysis examines whether the duration of chronic restraint stress affects behavioral test outcomes in rats, finding no correlation between duration and effect sizes.

This study shows that reelin administration reverses chronic stress-induced behavioral impairments without causing neuroinflammation in hippocampal microglia in rats.

The paper investigates how the BDNF intron-3 cis-regulatory element BE5.1 influences the effects of early-life stress on weight gain, anxiety, and gene expression, showing sex-dependent differences.

This study shows that the SERT genotype interacts with cumulative early-life stress to differentially affect anxiety-like behaviors in male and female rats.

The paper proposes the amygdala burnout hypothesis, showing early-life stress leads to initial amygdala volume increases in adolescence followed by reductions in older age across rodents and humans.

The paper links acute stress brain responses to everyday stress variability, finding greater variability correlates with stronger neural stress responses in specific brain regions.

The paper identifies disrupted CRH signaling as a cause of reward deficits after early-life stress and shows CRHR2 activation can reverse anhedonia-like behaviors.

This study shows that inhaled black carbon induces depressive-like behavior in mice and enhances molecular vulnerability under chronic stress.

This study identifies bile acid signaling as a pathway linking early caregiving adversity to social behavior, showing that CDCA supplementation can rescue social deficits in a rat model.

This study compares physiological, behavioral, and transcriptomic responses to chronic restraint stress in BALB/c and C57BL/6J mice, identifying strain-specific molecular signatures related to stress susceptibility.

This study examines how adult king penguins respond to chronic corticosterone exposure, finding they show resistance and resilience to its negative effects on physiology.

This study examines the effects of early postnatal aldosterone synthesis inhibition on behavior and stress response in male and female rats, finding sex-dependent changes in anxiety and adrenocortical regulation.

This study investigates stressor-specific patterns of noradrenaline release in the PVN of freely moving mice using a fluorescent sensor, revealing distinct temporal dynamics across different stressors.

This study shows that different stress types cause distinct plasma proteomic and metabolic responses in humans, with physical stress having the strongest effect.

The paper uses a computational model to show that slow stress-load accumulation, rather than BDNF-dependent feedback, drives coordinated changes in stress pathways under sustained stress.

This study shows that increasing circulating irisin through gene delivery protects mice from stress-induced social withdrawal without exercise.

The paper examines how trait resilience moderates the relationship between resting cortisol and aperiodic neural dynamics in the occipital scalp region.

This study shows that early maternal separation in rats increases prefrontal mitochondrial function and protects against stress-induced negative cognitive bias in adulthood.

This study shows that overnight Th1 immune activation, measured by neopterin, positively predicts the cortisol awakening response (CAR) in a small group of healthy subjects.

This study shows that gut-derived ammonia modulates hypothalamic stress responses during viral infection by increasing corticosterone levels and affecting antiviral responses.

This study investigates how early life stress affects probabilistic reversal learning in rats and examines the role of noradrenergic and serotonergic systems in modulating this effect.