Forensic and Genetic Research

hapCon estimates contamination in ancient DNA by analyzing male X chromosomes, outperforming existing tools in low coverage regimes.

The paper analyzes genome-wide SNP data from Southern Italy and neighboring regions to assess historical contacts and genetic affinities across the Adriatic Sea.

This report documents the successful extraction and analysis of ancient DNA from 27 African American individuals buried at Catoctin Furnace, Maryland, as part of a study on the enslaved and free African American population there.

The paper analyzes ancient genomes from Wallacea to show multiple human dispersals, with southern islands showing earlier Asian contributions than previously thought.

This study analyzes the genomes of Bruneian Malays using WGS and genotyping data, identifying novel variants and genomic sequences, and revealing genetic relationships with Filipino groups.

KLFDAPC improves geographic origin prediction by enhancing population separability and accuracy compared to PCA and DAPC.

This paper quantifies how allelic turnover affects polygenic score accuracy in ancient samples using theoretical models and simulations.

The paper analyzes ancient genetic data to trace the genetic connections between early Hungarians and populations from the Volga-Ural region between the 6th-14th centuries, revealing long-distance mobility and genetic continuity.

This paper develops a privacy-aware kinship inference method for admixed populations using reference panels and homomorphic encryption to protect genetic data.

This study evaluates genotype imputation for ancient DNA using Beagle 4.0 and 1000 Genomes reference data, showing high accuracy even at low coverage and highlighting the benefits of diverse reference sets and low-coverage samples.

This study presents the first whole genome sequences of pre-European contact Indigenous people from Uruguay, revealing connections to ancient Panama and eastern Brazil but not modern Amazonians, suggesting a distinct Atlantic coastal migration route.

This study shows that geography, not culture, mainly influences genetic variation among northern Kenyan populations.

This study analyzes the genetic structure of Newfoundland and Labrador using SNP data, revealing coastal community clustering, religious denomination associations, and a recent population bottleneck.

This study identifies loci under selection in Latin American admixed populations, distinguishing between pre- and post-admixture selection, and finds signals related to immunity and energy metabolism.

The paper derives properties of linkage disequilibrium and haplotype patterns in temporally structured samples, providing insights for analyzing ancient and modern genetic data.

SCOPE infers population structure in large genomic datasets efficiently and accurately, outperforming existing methods in speed while maintaining comparable accuracy.

The paper identifies 21 novel microhaplotype markers for ancestry inference in ten Chinese subpopulations, showing higher accuracy than SNP-based panels.

The paper analyzes genomic data from the Chabu, a hunter-gatherer group in Ethiopia, revealing a population bottleneck and diverse demographic responses to agropastoralism in East Africa.

This study identifies genomic signatures of adaptive admixture in 15 admixed populations, finding evidence of beneficial mutations acquired through population mixing.

This study clarifies the genetic origin and admixture history of the Tanka people using population genomic analysis of modern and ancient Eurasian samples.

The paper examines genetic heritage of the BaPhuthi to determine if KhoeSan ancestry reflects biological distinction or shared life-way, finding no unique eastern KhoeSan ancestry.

This study shows that PCA using a genetic relationship matrix is equivalent to MDS using nucleotide differences, offering a new method to predict demographic effects on genetic diversity.

This paper introduces a non-parametric method to infer human genealogical history from modern and ancient genomes, demonstrating its ability to reconstruct relationships and identify descendants of ancient samples.

The paper analyzes genetic data from Southeast Asian populations to identify Indian genetic heritage and its impact on local populations.

This paper introduces a method to reliably infer relatedness up to the 4-5th degree from low coverage ancient human genomes by addressing biases in kinship analysis.

This study analyzes ancient genomes from Bronze Age Hungary, revealing complex population histories, high hunter-gatherer ancestry in some groups, and new methods for ancient DNA analysis.

The paper analyzes genetic structure in Brittany and the Loire basin to understand Western Europe's demographic history, finding increased population differentiation linked to steppe and Neolithic ancestry.

The paper describes the continental ancestry and population structure of non-white British individuals in the UK Biobank using reference populations and clustering methods.

The paper sequences 24 ancient Brazilian genomes, including 22 Botocudos, revealing Indigenous American ancestry without external gene flow and low heterozygosity, and identifies ancient pathogen lineages.

This paper shows that natural selection does not affect estimates of effective population size from linkage disequilibrium, while coalescence methods are influenced by selection.