Topic · Structural Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
666 papers
Eveline Ultee, Fred Schenkel, Wen Jing Yang…·Ariane Briegel
The paper presents an open-source cryo-storage system to improve sample storage efficiency and organization in cryo-EM laboratories.
Manuela K. Hospenthal, Dawid S. Zyla, Tiago R. D. Costa…·Gabriel Waksman
The paper presents the cryo-EM structure of the type 1 chaperone-usher pilus rod at 4.2 Å resolution, revealing its spring-like biomechanical properties.
Zachary T. Berndsen, Charles Bowman, Haerin Jang, Andrew B. Ward
The paper introduces EMHP, an automated hole masking algorithm for single-particle cryo-EM image processing to streamline data treatment.
Javier Vargas, Roberto Melero, Josué Gómez-Blanco…·Carlos Óscar S. Sorzano
This work introduces a soft-alignment validation method to assess alignment precision, accuracy, and data homogeneity in cryo-EM single particle analysis, improving map resolution through data quality enhancement.
Robert A. McLeod, Ricardo Diogo Righetto, Andy Stewart, Henning Stahlberg
The paper proposes a compressed MRC file format and normalization strategies for direct electron detectors to improve data storage and reduce noise in transmission electron microscopy.
Shaoda He, Sjors H. W. Scheres
RELION 2.0 adds empirical Bayesian helical reconstruction with orientation priors, filament-level half-sets and local twist/rise optimisation, yielding near-atomic maps for four filament datasets.