Bacteriophages and microbial interactions

This study shows that the virus {Psi}M2 can enter a non-lytic lifecycle alternative to lysogeny in Methanothermobacter marburgensis under suboptimal conditions, with genetic variability in viral populations.

The paper uses epidemiological models to identify molecular mechanisms of antiviral resistance in phytoplankton from experimental data.

This study identifies Htm, a phage-encoded protein that reprograms the transcriptome of ESBL-E. coli to support phage replication by altering gene expression and metabolic pathways.

The paper analyzes Phycodnaviridae viral homologs of heme oxygenase-1 and Phycocyanobilin:Ferredoxin oxidoreductase to predict their subcellular localization and functional divergence from host enzymes.

The paper identifies a conserved viral protein module that displaces host RNA polymerase sigma factors to control transcription in mycobacteria.

This study identifies novel antiviral defense systems in Streptococcus thermophilus by analyzing genomic islands, revealing previously uncharacterized systems and highlighting their role as reservoirs of bacterial immunity.

The paper shows that HHQ enables Gephyrocapsa huxleyi to evade viral lysis by remodeling host processes, not by inhibiting viral transcription.

The paper identifies three new families of archaeal extrachromosomal elements and shows their relatedness is due to horizontal gene transfer, not common ancestry.

The paper investigates phage activity during vegetable fermentation and shows phages influence bacterial succession without disrupting fermentation stability.

The paper tracks gene flow in the gut microbiome, showing diet and community ecology influence phage activation and horizontal gene transfer.

The paper investigates how prophage costs and competitive benefits shape bacterial evolution in polymicrobial environments, finding environment-dependent adaptive strategies and trade-offs.

This study identifies Rhc as a multifunctional protein essential for DNA replication and transcription in nucleus-forming phages, revealing its role in resolving R-loops and coordinating gene expression.

This study identifies a unique DNA replication mechanism in the chimallivirus PhiKZ, where a sliding clamp-derived protein enhances polymerase activity through a transient interaction.

This study identifies Tiamat as an ATPase and DNase in bacteria and shows its homologs are widespread across eukaryotes, with some acquiring non-defense roles.

The paper identifies a novel virus lineage, IME1, found in Dehalococcoides-containing cultures, characterized by features similar to filamentous bacterial viruses.

The paper investigates how season and fertilization affect soil microbiome dynamics and interactions with Bdellovibrio-and-Like Organisms (BALOs) in agricultural fields.

This study uses time-lapse imaging to analyze phage infection dynamics in bacteria, revealing heterogeneity and its impact on phage fitness.

The paper isolates and characterizes a new jumbo Klebsiella phage, BMCPR_005026, identifying it as a new species within the Alcyoneusvirus genus with limited host range.

The paper shows that RecBCD clears self-DNA ends during bacterial replication termination to prevent autoimmunity, similar to TREX1 and DBR1 in eukaryotes.

Two polinton-like viruses, Larry and Curly, replicated in C. parva cultures only with the Algavirales phycodnavirus CpV-BQ1, not with the Imitervirales virus CpV-BQ3, and they reduced BQ1 replication.

This study characterizes 30 lytic Klebsiella pneumoniae bacteriophages, finding diverse genomic structures and no virulence or antibiotic resistance genes, with potential as antimicrobial agents against carbapenem-resistant K. pneumoniae.

The paper identifies capsule types in carbapenem-resistant Klebsiella pneumoniae from Pakistan that lack corresponding phages, highlighting regional disparities in phage coverage.

The paper reconstructs the MS2 phage genome using cDNA and shows that the current NCBI reference genome does not produce infectious phage, highlighting the need to verify reference genome infectivity.

The paper investigates how viral anti-defense systems vary with genomic traits, host immunity, and environmental stress across microbial ecosystems.

The paper examines the association between phage and antibiotic resistance in Pseudomonas aeruginosa clinical isolates and finds a positive correlation between the two resistance phenotypes.

This study identifies a bacterial protease that influences phage susceptibility and links it to host epithelial responses in ulcerative colitis.

This study investigates how giant virus and virophage co-infection alter the host lipidome, finding distinct lipid remodeling patterns associated with each infection type.

CheckAMG identifies auxiliary viral genes by combining annotation-based prediction with a genome-language model, improving accuracy and uncovering novel genes with no sequence similarity to references.

This study investigates how Burkholderia thailandensis responds to antibiotics and phages in spatial refuges, revealing distinct subpopulation behaviors and interactions.

This study shows that loss of type I restriction-modification methyltransferases in Pseudomonas aeruginosa increases fluoroquinolone persistence through enhanced SOS response and slower growth.