3D Printing in Biomedical Research

This study develops 3D printed PEDOT:PSS hydrogel scaffolds with soft tissue-like stiffness to support cell viability and function in bioelectronic applications.

This study develops and characterizes bioinks for 3D bioprinting skeletal muscle models, finding that nanofiber cellulose with fibrinogen supports myoblast growth and differentiation into mature myotubes.

This paper introduces Xolography, a dual-color light-sheet printing technique, to create hydrogels with controlled shape and stiffness for biomedical applications.

This study uses automated cell dispensing to create 3D cancer cell models for high throughput screening, showing minimal impact on cell behavior and improved efficiency.

This study develops a microfluidic human skin equivalent to replicate dynamic immune responses, showing monocyte recruitment and gene expression patterns similar to in vivo inflammation.

The paper introduces an open microfluidic microtumor model combining top-down and bottom-up strategies to study tumor cell-ECM interactions and test anti-metastasis drugs.

This paper develops DigiLoCS, a digital twin model for liver-on-chip systems to predict human drug clearance and bridge in vitro to clinical relevance.

This study shows dicarbonyl stress increases cancer cell intravasation by degrading ECM and promoting endothelial dysfunction in a microfluidic model.

This paper develops a 3D bioprinted liver fibrosis model using GelMA and dECM, validated with methotrexate to induce fibrosis and assess functional and molecular changes.

This paper introduces a Brain Organoid-on-a-Chip platform that generates signaling gradients to create topographic forebrain organoids, mimicking human brain regions for neurodevelopment and disease studies.

The paper presents a microfluidic organ-on-chip method to study immune cell responses to drug-treated tumor cells in 3D.

This paper introduces a thermoplastic chip for single-cell immune assays that enables screening and high-resolution imaging of immune cell responses in 2D and 3D cultures.

This paper introduces a lung tumor-on-a-chip model that simulates hypoxia and evaluates its impact on radiotherapy response and FDG-PET imaging.

This study develops a light-based bioprinting method using decellularized extracellular matrix to create anisotropic cartilage scaffolds that promote tissue maturation and mimic native structure.

The paper develops a toxicokinetic model to measure and predict chemical-PDMS interactions in organ-on-chip devices, showing accurate dose prediction under continuous-flow conditions.

This study investigates how microfluidic flow parameters affect solute transport in 3D cell cultures, showing that chamber size, inlet velocity, and confinement influence solute distribution and penetration depth.

This study shows that pancreatic ductal adenocarcinoma cells in collagen droplets form branched organoids with complex morphology, suggesting accelerated maturation compared to traditional bulk culture.

This study develops tunable porcine skin-derived hydrogels for 3D bioprinting, optimizing their mechanical properties and printability to support cellular growth and structure formation.

This paper presents a low-cost, open-access 3D-printed Gut-on-Chip method for gut research, demonstrating its functionality with Caco-2 cells.

This study enhances the maturity and functionality of liver organoids by combining 3D bioprinting with vascular progenitor cells and a pillar plate culture system.

This study develops a 4D bioprinted self-folding scaffold that enhances cartilage formation in engineered trachea by enabling eCPCs to respond to scaffold curvature.

This paper develops a 3D in vitro kidney model with immune cells to study inflammation and injury, showing monocyte migration and response to inflammatory stimuli.

This paper presents 3D printed microstructured alginate scaffolds with tetrapod-shaped ZnO templates that enhance neuron adhesion and maturation.

This paper develops a hybrid bioink combining self-assembled peptides and alginate to create a stiff, printable, and self-healing material with improved biocompatibility for tissue engineering and biosensing.

This study develops a microfluidic chip model of endochondral ossification using human stem cell-derived organoids, showing vascular-like network formation and interactions.

This paper develops a 3D-printed organ-on-chip platform with a tubing-free pump to model lymph node communication during vaccination.

This paper develops a high-throughput microfluidic system to generate reproducible 3D leukemia microenvironments for drug testing, showing that stroma-leukemia interactions protect cells from drug-induced cytotoxicity.

This paper develops a method to create serially perfusable multiscale capillary beds in vitro for studying vascular biology and integration into organoid and organ-on-a-chip models.

This study develops a method to fabricate and assemble organoid units for creating larger, transplantable organ-like structures.