Zebrafish Biomedical Research Applications

The paper describes an optimized pipeline for genotyping zebrafish embryos after in situ hybridization and digitally quantifying gene expression, improving accuracy and reducing bias.

The paper develops a dynamic circuit model to explain how heat sensation is transformed into swimming behavior in larval zebrafish.

This study develops a technique to image whole brain neural activity in freely behaving larval zebrafish during specific behaviors.

This study uses microCT to analyze zebrafish skeletons, identifying phenotypes linked to human diseases and showing how deep phenotyping improves mutant discrimination.

This study aligns two zebrafish brain atlases using symmetric diffeomorphic normalization, improving registration precision and preserving morphology.

The study identifies organ-specific cardiovascular functions and mechanisms in zebrafish, revealing why the cardiovascular system develops first.