Zebrafish Biomedical Research Applications

This study develops a technique to image whole brain neural activity in freely behaving larval zebrafish during specific behaviors.

This study shows larval zebrafish use independent volitional and reflexive movements for locomotion, revealing a simple control scheme that enables effective but inflexible swimming.

This study uses microCT to analyze zebrafish skeletons, identifying phenotypes linked to human diseases and showing how deep phenotyping improves mutant discrimination.

This study aligns two zebrafish brain atlases using symmetric diffeomorphic normalization, improving registration precision and preserving morphology.

This paper presents a single-step genotyping protocol for paraformaldehyde-fixed zebrafish embryos, enabling reliable genotyping of lethal mutants.

The paper investigates how hypoxia-induced VEGF signaling promotes caudal fin regeneration in zebrafish through angiogenesis and wound healing.

scartrace uses Cas9-induced genetic scars for clonal analysis in zebrafish, aiming at lineage reconstruction across many cells at once rather than the small subsets imaging covers.

The study identifies organ-specific cardiovascular functions and mechanisms in zebrafish, revealing why the cardiovascular system develops first.