Poxvirus research and outbreaks

The paper identifies a distinct phylogenetic cluster of monkeypox virus genomes, lineage A.2, which differs from the dominant lineage B.1 associated with the 2022 European outbreak.

The paper analyzes mutations in hMPXV1 genomes to identify clustering patterns and sequence context, suggesting APOBEC-mediated editing as the mutational mechanism.

The paper analyzes five Monkeypox virus genomes to identify gene duplications and losses as potential adaptations to the human host during the 2022 outbreak.

The paper describes an amplicon-based method for sequencing Monkeypox virus genomes using MinION Nanopore technology, achieving high-quality results even from samples with high Ct values.

The paper identifies two lineages of Monkeypox virus in the U.S. in 2021-2022, finding a common ancestor and evidence of APOBEC3 editing in West African strains.

The paper evaluates the efficacy of UV-C disinfection against vaccinia, a surrogate for monkeypox, showing over 99.996% virucidal efficacy in under 7 minutes.

The paper identifies increased transmissibility in MPXV clade IIb by analyzing genomic low-complexity regions (LCRs) and suggests they may be more informative than SNPs.

The paper identifies large genomic deletions and rearrangements in monkeypox virus from the 2022 outbreak in the USA, highlighting potential implications for diagnostic testing.

The paper introduces a web-scraped skin image dataset for Monkeypox, Chickenpox, Smallpox, Cowpox, Measles, and healthy skin to aid in machine learning-based early detection of Monkeypox.

The paper analyzes genome sequences from the 2022 European monkeypox outbreak to identify genetic variability, including gene duplication and deletion, and their potential role in viral adaptation.

This study analyzes mutations in the Monkeypox virus during the 2022 outbreak, identifying six new mutations and their potential impact on host-pathogen interactions and viral fitness.

This paper identifies a genomic mutation in monkeypox virus linked to increased transmission by analyzing the evolution of a G-quadruplex structure in the C9L gene.

The paper was withdrawn due to lack of data use authorizations and is not to be cited as reference.

The paper analyzes the innate immune response at injection sites after vaccination with a recombinant vaccinia vector, identifying immune signatures and gene expression patterns.

This paper uses next-generation sequencing to analyze cowpox virus outbreaks in humans and cats, finding high clonality in a human outbreak and partial transmission in a feline outbreak.