thermodynamics and calorimetric analyses

This study evaluates a novel isothermal microcalorimetry-based sterility test, finding it more sensitive and faster than the traditional USP sterility test.

The paper examines how small temperature variations in enzyme activation parameters affect Arrhenius/Eyring modeling, leading to apparent enthalpy-entropy compensation and misinterpretation of kinetic data.

This study measures metabolic heat output of individual Drosophila brains to examine effects of sex, genotype, age, and disease on brain metabolism.

The paper introduces a fluorescence-based method to quantify drug-target engagement in temperature series using split-RNase S complementation.

This paper develops an ITC assay to measure kinetic and inhibition parameters of SARS-CoV-2 3CL-protease, revealing two inhibition modes and deriving kinetic constants with high precision.

This paper examines the thermodynamics of biomolecular interactions using a governing equation that includes solvation free energy, showing its impact on DNA hybridization, protein-ligand binding, and protein folding.

This paper provides a detailed protocol for producing LIR peptides and using ITC to study their interactions with LC3/GABARAP proteins, including troubleshooting guidance.

CalR is a web-based tool for analyzing indirect calorimetry data, offering statistical analysis, visualization, and standardized output to improve reproducibility and efficiency in metabolic experiments.