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StrataChip enables dynamic study of human epidermal morphogenesis by integrating microfluidics with single-cell RNA-sequencing and imaging, revealing transcriptional and mechanical transitions during stratification.

This study develops and tests IL12-engineered human PSMA-CAR T cells for advanced prostate cancer, showing improved anti-tumor activity and safety.

This paper introduces a stencil-based method to create 2D microtissue co-cultures with spatial precision, demonstrating applications in tumor microenvironment modeling, morphogen gradient studies, and intestinal architecture recreation.

This study assesses arrhythmic risk from engineered heart tissue implantation in porcine hearts with different infarct locations using computational models.

This paper introduces a computational pipeline to predict brain swelling after stroke using a mathematical model and deep neural network, achieving an AUC of 0.7 in predicting 3-month outcomes.

This paper describes a method using a nanofiber scaffold to deliver mesangioblasts systemically, restoring dystrophin expression in DMD mice.

The paper evaluates the variability of GAMLSS-based brain charts using analytic and empirical methods, finding low coefficient of variation across most white matter features.

This paper develops a digital-twin framework for fungal excitable networks to identify viable XOR computation regimes and refine biophysical parameters using waveform matching.

This paper uses optogenetic control of RET signaling to induce controlled budding in human kidney organoids.

This paper develops a 3D-printed bioadhesive patch with electrical and mechanical properties to modulate cardiac tissue repair and immune responses.

This study shows that physical continuity between biomaterials and the extracellular matrix reduces fibroblast activation and fibrosis by inhibiting NF-κB signaling.

This study develops a nanoparticle system to deliver Panobinostat intrathecally for treating metastatic medulloblastoma, showing improved drug distribution and survival benefits in mice.

This paper identifies gut bacteria that stereoselectively synthesize neurosteroid isomers using a plant-based medium, achieving high conversion and purity without chiral purification.

This paper develops two complementary multiphoton-based biofabrication tools to create tunable hydrogel curvatures for epithelial tissue engineering, showing enhanced cytoskeletal organization and cell shape formation.

This paper introduces a flexible skull-conformal phased array for transcranial focused ultrasound therapy, demonstrating improved focusing and aberration correction in a human skull.

This study investigates how different TMS intensities affect stretch-evoked long-latency responses in the flexor carpi radialis, finding that only suprathreshold TMS inhibits these responses via a cortical silent period.

This paper develops a DNA tetrahedron conjugated with alpha-tocopherol to enhance cellular uptake and selectively kill cancer cells through ROS-induced apoptosis.

This study evaluates the Segregostat system's ability to control stress responses in microbial cells under industrial bioreactor conditions using automated flow cytometry.

This study shows that systemic inflammation significantly prolongs EV plasma half-life and enhances their accumulation in inflamed organs like the liver and spleen.

The paper develops RPSPASS, a software tool for automated analysis of microfluidic nanoparticle data, improving accuracy, ergonomics, and reporting transparency.