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A fuzzy sequencer improves information efficiency and accuracy in DNA resequencing applications.

The paper examines age-related DNA methylation changes in beta and alpha cells using HPAP data, finding accelerated demethylation in T2D beta cells.

This study uses long-read nanopore sequencing of cell-free RNA to detect early-stage cancer and discover novel biomarkers, identifying 270,679 intergenic RNAs and potential therapeutic targets.

The paper investigates the phenotypic effects of rDNA copy number variation in C. elegans using recombinant inbred lines and finds no significant correlation with key phenotypes.

The paper applies SHAPE-MaP to identify functional RNA structures in PEDV to guide antiviral drug design.

This study investigates how music affects gene expression and methylation in traumatic brain injury by comparing transcriptomic and epigenomic data from healthy individuals and TBI patients.

The paper introduces an updated DNA barcoding tool for Aloe vera and related CITES-regulated species, validated for accurate species identification using 189 nuclear markers.

The paper investigates viral lateral gene transfer in Acanthamoeba, showing viral insertions are epigenetically silenced and subject to deterioration over time.

This study identifies ox-LDL-induced non-inflammatory changes in endothelial cells that are enriched for coronary artery disease risk.

The paper introduces Dam&ChIC, a method for time-resolved chromatin profiling in single cells, revealing that genome-lamina detachment precedes H3K27me3 accumulation during X-chromosome inactivation.

The paper investigates microbial communities in three wild tick species to understand how ecological and evolutionary factors shape their microbiota.

This study identifies DNA methylation changes in sows related to parity and environmental enrichment, suggesting epigenetic adaptation and potential biomarkers for affective states.

This study identifies the role of H3K9 methyltransferases in maintaining centromere compartmentalization by regulating CENP-A and heterochromatin distribution.

The paper uses single-cell 3D genome mapping to show cohesin-mediated loop extrusion forms transcription elongation loops that enhance transcriptional burst frequency.

The paper uses machine learning to predict antigenic properties of influenza A(H3) virus from genomic data, finding that deep learning models outperform classical methods in fine-grained antigenic analysis.

The paper presents high-quality genome assemblies for two olive cultivars using PacBio HiFi sequencing, revealing structural differences in genes related to salt stress.

The paper identifies and quantifies compensatory evolution following deleterious gBGC episodes in rodents, showing rapid repair through standing genetic variation.

The paper shows hypoxia impairs differentiation of cranial neural crest cells into chondrocytes, osteoblasts, and smooth muscle cells, linking it to orofacial cleft risk.

The paper benchmarks structural variant callers in cancer genomics and recommends a consensus approach combining Delly, GRIDSS, Manta, and SvABA for improved performance.

The paper identifies evolutionary patterns in the human brain epigenome using single-cell ATAC-seq data, revealing lineage-specific regulatory changes and their association with brain disease variants.