Author

A. A. Salahudeen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. J. Kuo· 3 shared A. Batish· 2 shared D. J. Hart· 2 shared S. M. De la O· 2 shared T. J. Desai· 2 shared T. Usui· 2 shared A. J. M. Santos· 1 shared A. M. Dudek· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

C. J. Kuo

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Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 5, 2021

Pan-cancer organoid validation of tumor outlier chromosomal amplification events

A. A. Salahudeen, K. Yuki, J. Seoane…·C. J. Kuo

The paper validates oncogenic chromosomal amplification events across multiple cancers using organoid models and functional assays.

DOI 10.1101/2021.10.05.463147

𝕏 PostBluesky

BioengineeringbioRxivFeb 26, 2021

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus

S. Vaidyanathan, R. Baik, L. Chen…·M. Porteus

This study corrects multiple CFTR mutations in human airway stem cells using CRISPR/Cas9 and AAV vectors, achieving functional restoration in differentiated epithelial cells.

DOI 10.1016/j.ymthe.2021.03.023

humanCRISPR screen

𝕏 PostBluesky

Cell BiologybioRxivPreprintJul 27, 2020

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

A. A. Salahudeen, S. S. Choi, A. Rustagi…·C. J. Kuo

This paper develops a feeder-free organoid culture system for human distal lung progenitors and demonstrates SARS-CoV-2 infection of club cells in a novel in vitro model.

DOI 10.1101/2020.07.27.212076

𝕏 PostBluesky