Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.
C. A. Headley, S. Gautam, A. M. Olmo-Fontanez, A. M. Garcia-Vilanova, V. Dwivedi, A. Akhter, A. Schami, K. Chiem, R. Ault, H. Zhang, H. Cai, A. A. Whigham, J. A. Delgado, A. A. Hicks, P. Tsao, , J. Turner
This study transfers functional mitochondria into aged CD4+ T cells, improving their metabolism, reducing oxidative stress, and enhancing immune function against infections.
bioRxiv · Feb 21, 2021Immunology