Author

R. Ault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. A. Hicks· 1 shared A. A. Whigham· 1 shared A. Akhter· 1 shared A. J. Borst· 1 shared A. M. Garcia-Vilanova· 1 shared A. M. Olmo-Fontanez· 1 shared A. Schami· 1 shared B. Huang· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. A. Hicks

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Author profile →

2 papers

Recent·Most cited

Atomically accurate de novo design of antibodies with RFdiffusion

N. R. Bennett, J. L. Watson, R. J. Ragotte, A. J. Borst, D. L. See, C. Weidle, R. Biswas, Y. Yu, E. L. Shrock, R. Ault, P. J. Y. Leung, B. Huang, I. Goreshnik, J. Tam, K. D. Carr, , D. Baker

This paper designs antibodies de novo with atomic precision using RFdiffusion and yeast display, validated by cryo-EM and biophysical methods.

bioRxiv · Mar 14, 2024Bioengineering

Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging.

C. A. Headley, S. Gautam, A. M. Olmo-Fontanez, A. M. Garcia-Vilanova, V. Dwivedi, A. Akhter, A. Schami, K. Chiem, R. Ault, H. Zhang, H. Cai, A. A. Whigham, J. A. Delgado, A. A. Hicks, P. Tsao, , J. Turner

This study transfers functional mitochondria into aged CD4+ T cells, improving their metabolism, reducing oxidative stress, and enhancing immune function against infections.

bioRxiv · Feb 21, 2021Immunology