Author

A. Aktipis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:ecology & biodiversity· 2 Organism:multiple species· 2 Organism:Drosophila· 1 Organism:mouse· 1

Frequent Co-Authors

C. C. Maley· 3 shared A. Fortunato· 2 shared A. M. Boddy· 2 shared C. Maley· 2 shared E. G. Duke· 2 shared M. Tollis· 2 shared O. Vincze· 2 shared S. Aksoy· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

C. C. Maley

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Author profile →

6 papers

Recent·Most cited

Cancer Prevalence Across Vertebrates

Z. T. Compton, W. Mellon, V. Harris, S. Rupp, D. Mallo, S. Kapsetaki, M. Wilmot, R. Kennington, K. Noble, C. Baciu, L. Ramirez, A. Peraza, B. Martins, S. Sudhakar, S. Aksoy, , A. Boddy

The paper analyzes cancer prevalence across 292 vertebrate species and finds that neoplasia prevalence increases with adult weight and mutation rate but decreases with gestation time.

bioRxiv · Feb 15, 2023Cancer Biology

Life history and cancer in birds: clutch size predicts cancer

S. E. Kapsetaki, Z. Compton, J. Dolan, V. K. Harris, S. M. Rupp, E. G. Duke, T. M. Harrison, S. Aksoy, M. Giraudeau, O. Vincze, K. J. McGraw, A. Aktipis, M. Tollis, A. M. Boddy, C. C. Maley

This study investigates the relationship between life history traits and cancer prevalence in managed birds, finding that clutch size is positively correlated with cancer and neoplasia prevalence.

bioRxiv · Feb 11, 2023Cancer Biology

The ecology of cancer prevalence across species: Cancer prevalence is highest in desert species and high trophic levels

S. E. Kapsetaki, Z. Compton, S. M. Rupp, M. M. Garner, E. G. Duke, A. M. Boddy, T. M. Harrison, A. Aktipis, C. C. Maley

The paper examines cancer prevalence across 244 vertebrate species, finding higher rates in high trophic levels and low productivity habitats, though only trophic level correlations remained significant after corrections.

bioRxiv · Aug 23, 2022 · PreprintCancer Biology

Sponges are highly resistant to radiation exposure and cancer

A. Fortunato, J. Taylor, J. Scirone, A. Aktipis, C. Maley

This study exposes sponges to high radiation doses and finds they resist cancer, with overexpressed DNA repair genes and no cancer induction.

bioRxiv · Mar 17, 2021 · PreprintEvolutionary Biology

Upregulation of DNA repair genes and cell extrusion underpin the remarkable radiation resistance of Trichoplax adhaerens.

A. Fortunato, A. Fleming, A. Aktipis, C. C. Maley

This study identifies DNA repair gene upregulation and cell extrusion as mechanisms enabling Trichoplax adhaerens to resist high radiation levels.

bioRxiv · Dec 24, 2020Cancer Biology

Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

S. Naffar-Abu Amara, H. J. Kuiken, L. M. Selfors, T. Butler, M. L. Leung, C. T. Leung, E. P. Kuhn, T. R. Kolarova, C. Hage, K. Ganesh, R. Foster, B. R. Rueda, A. Aktipis, P. T. Spellman, T. Ince, , J. S. S. Brugge

The paper shows that transient interactions between non-tumorigenic and tumorigenic clones can drive metastasis through amphiregulin-mediated mesothelial clearance.

bioRxiv · Jan 16, 2020 · PreprintCancer Biology