Author

A. Alavizargar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Approach:mechanistic / dynamical model· 2 Approach:statistical model· 2 Organism:yeast· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Heuer· 4 shared F. Keller· 2 shared A. Elting· 1 shared M. Gass· 1 shared M. P. Krahn· 1 shared R. Wedlich Soeldner· 1 shared R. Wedlich-Soeldner· 1 shared R. Wedlich-Soldner· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 11 mutual co-author links

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4 shared papersBiophysics

A. Heuer

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Author profile →

4 papers

Recent·Most cited

BiophysicsbioRxivAug 2, 2023

Elucidating the Membrane Binding Process of a Disordered Protein: Dynamic Interplay of Anionic Lipids and the Polybasic Region

A. Alavizargar, M. Gass, M. P. Krahn, A. Heuer

This study uses MD simulations and cell culture experiments to show that LKB1's polybasic motif binds anionic lipids dynamically, with key residues and thermodynamic insights provided by a statistical model.

DOI 10.1021/acsphyschemau.3c00051

humanproteomics

𝕏 PostBluesky

BiophysicsbioRxivJul 27, 2022

Impact of bilayer composition on the dimerization properties of the Slg1 stress sensor TMD from a multiscale analysis

F. Keller, A. Alavizargar, R. Wedlich-Soeldner, A. Heuer

This study evaluates how bilayer composition affects TMD dimerization using multiscale simulations, finding that ergosterol and phospholipid composition influence TMD-TMD and TMD-lipid interactions.

DOI 10.1039/d2cp03497b

yeastspatial transcriptomics

𝕏 PostBluesky

BiophysicsThe Journal of Physical Chemistry BPeer-reviewedJul 22, 2021

Effect of Cholesterol vs. Ergosterol on DPPC Bilayer Properties: Insights from Atomistic Simulations

A. Alavizargar, F. Keller, R. Wedlich-Soldner, A. Heuer

This study compares the effects of cholesterol and ergosterol on DPPC bilayer properties using molecular dynamics simulations, finding cholesterol has a stronger impact due to its planarity and molecular interactions.

DOI 10.1021/acs.jpcb.1c03528

mechanistic / dynamical model

𝕏 PostBluesky

BiophysicsbioRxivJun 29, 2021

Lipid-mediated Association of the Slg1 Transmembrane Domains in Yeast Plasma Membranes

A. Alavizargar, A. Elting, R. Wedlich Soeldner, A. Heuer

This study investigates how lipid composition influences transmembrane domain (TMD) dimerization in yeast plasma membranes using simulations and live-cell microscopy.

DOI 10.1021/acs.jpcb.2c00192

yeastfluorescence / live-cell microscopy

𝕏 PostBluesky