Author

F. Keller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:imaging· 2 Assay:spatial transcriptomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

R. Rudolf· 3 shared A. Alavizargar· 2 shared A. Heuer· 2 shared C. Hopf· 2 shared S. A. Iakab· 2 shared S. Schmidt· 2 shared A. Agaci· 1 shared D. Abu Sammour· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

R. Rudolf

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Multiparametric Analysis Reveals Differential Behavior of Spheroid Cultures on Distinct Ultra-Low Attachment Plates Types

M. Vitacolonna, R. Bruch, A. Agaci, E. Nuernberg, T. Cesetti, F. Keller, F. Padovani, S. Sauer, K. M. Schmoller, M. Reischl, M. Hafner, R. Rudolf

This study compares spheroid formation and behavior across six ultra-low attachment plate types using four human cell lines, finding size and eccentricity differences that suggest plate type impacts experimental outcomes.

bioRxiv · Mar 26, 2024 · PreprintCancer Biology

Deep MALDI-MS Spatial Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy

L. Gruber, S. Schmidt, T. Enzlein, H. G. Vo, J. L. Cairns, Y. Ucal, F. Keller, D. Abu Sammour, R. Rudolf, M. Eckhardt, S. A. Iakab, L. Bindila, C. Hopf

This paper introduces a method combining quantum cascade laser infrared imaging with mass spectrometry to improve molecular identification in spatial omics, achieving high-resolution lipidomics profiling.

bioRxiv · Dec 14, 2023Biochemistry

3D-Mass Spectrometry Imaging of Micro-scale 3D Cell Culture Models in Cancer Research

S. A. Iakab, F. Keller, S. Schmidt, J. Cordes, Q. Zhou, J. J. Cairns, F. Fischer, R. Schneider, I. Wolf, R. Rudolf, C. Hopf

The paper presents a 3D-MSI platform for analyzing lipid distribution in 3D cell cultures, revealing metabolic interactions in cancer models.

bioRxiv · Dec 5, 2022 · PreprintCancer Biology

Impact of bilayer composition on the dimerization properties of the Slg1 stress sensor TMD from a multiscale analysis

F. Keller, A. Alavizargar, R. Wedlich-Soeldner, A. Heuer

This study evaluates how bilayer composition affects TMD dimerization using multiscale simulations, finding that ergosterol and phospholipid composition influence TMD-TMD and TMD-lipid interactions.

bioRxiv · Jul 27, 2022Biophysics

Effect of Cholesterol vs. Ergosterol on DPPC Bilayer Properties: Insights from Atomistic Simulations

A. Alavizargar, F. Keller, R. Wedlich-Soldner, A. Heuer

This study compares the effects of cholesterol and ergosterol on DPPC bilayer properties using molecular dynamics simulations, finding cholesterol has a stronger impact due to its planarity and molecular interactions.

The Journal of Physical Chemistry B · Jul 22, 2021Peer-reviewedBiophysics