Pharmacology & ToxicologybioRxiv
Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo
K. Ernst, A.-K. Mittler, V. Winkelmann…·H. Barth
The paper investigates how host chaperones facilitate pertussis toxin uptake and shows that pharmacological inhibition of these chaperones protects cells from PT toxicity.