Author

K. Ernst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

A. Anastasia· 1 shared A. Harant· 1 shared A. Posbeyikian· 1 shared A. Toghani· 1 shared A. Verhage· 1 shared A.-K. Mittler· 1 shared C. Herold-Mende· 1 shared C. Skerry· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Anastasia

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A root-specific NLR network confers resistance to plant parasitic nematodes

D. Luedke, T. Sakai, J. Kourelis, A. Toghani, H. Adachi, A. Posbeyikian, R. Frijters, H. Pai, A. Harant, K. Ernst, M. Ganal, A. Verhage, C.-H. Wu, S. Kamoun

The paper identifies a root-specific NLR gene cluster in tomato that confers resistance to nematodes and evolved from an ancient NRC network.

bioRxiv · Dec 14, 2023 · PreprintPlant Biology

A connectivity signature for glioblastoma

L. Hai, D. C. Hoffmann, H. Mandelbaum, R. Xie, J. Ito, E. Jung, S. Weil, P. Sievers, V. Venkataramani, D. D. Azorin, K. Ernst, D. Reibold, R. Will, M. L. Suva, C. Herold-Mende, , T. Kessler

This paper establishes and validates a connectivity signature in glioblastoma using scRNA-Seq data, showing high connectivity correlates with poor patient survival and specific molecular subtypes.

bioRxiv · Nov 7, 2021 · PreprintCancer Biology

Pharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo

K. Ernst, A.-K. Mittler, V. Winkelmann, N. Eberhardt, A. Anastasia, M. Sonnabend, R. Lochbaum, J. Wirsching, C. Skerry, N. H. Carbonetti, M. Frick, H. Barth

The paper investigates how host chaperones facilitate pertussis toxin uptake and shows that pharmacological inhibition of these chaperones protects cells from PT toxicity.

bioRxiv · Sep 24, 2020Pharmacology & Toxicology