Confinement with Myosin-II suppression increases heritable loss of chromosomes, using live-cell ChReporters
B. Hayes, P. Zhu, M. Wang, C. Pfeifer, Y. Xia, S. Phan, J. Andrechak, J. Du, M. Tobin, A. Anlas, L. Dooling, J. Irianto, M. Lampson, D. Discher
The paper uses live-cell ChReporters to show that Myosin-II suppression in confined mitosis increases heritable chromosome loss, independent of spindle assembly checkpoint in 3D and 2D.
bioRxiv · Feb 25, 2023 · PreprintCell Biology