Author

A. Astrinidis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

E. Y. Zhang· 2 shared J. J. Yu· 2 shared A. A. Zhang· 1 shared C. Li· 1 shared D. L. Johnson· 1 shared D. Lindquist· 1 shared E. Fugate· 1 shared E. J. Kopras· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

E. Y. Zhang

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Combination of Volasertib and Rapamycin Inhibits the Regrowth of TSC2-Deficient Tumors

M. Valianou, E. Y. Zhang, D. L. Johnson, R. Meyers, M. M. Markiewski, M. Karbowniczek, L. M. Pfeffer, J. J. Yu, J. J. Bissler, A. Astrinidis

This study shows that combining volasertib and rapamycin inhibits tumor regrowth in TSC2-deficient models more effectively than rapamycin alone.

bioRxiv · Nov 2, 2022 · PreprintCancer Biology

Dysregulation of Acid Ceramidase-mediated Sphingolipid Metabolism Contributes to Tumor Progression in Tuberous Sclerosis Complex

A. Astrinidis, C. Li, E. Y. Zhang, X. Zhao, S. Zhao, M. Guo, R. Huang, A. A. Zhang, E. J. Kopras, N. Gupta, E. P. Smith, E. Fugate, D. Lindquist, K. Wikenheiser-Brokamp, K. D. Setchell, , J. J. Yu

This study identifies dysregulated sphingolipid metabolism in TSC2-null cells and tumors, showing that ASAH1 inhibition reduces cell viability and tumor growth in TSC and LAM.

bioRxiv · Sep 25, 2022 · PreprintCell Biology