Single-Cell Transcriptomic Analyses of Tumor Ecosystems and Spatial Architectures in Human Small Cell Lung Cancers
H. Ouyang, J. Chen, C. Xu, C. He, L. Sheng, J. Wang, D. Pan, A. Augert, J. Lin, Y. Zhu, D. Jia
This study uses single-cell and spatial transcriptomics to analyze heterogeneity and immunosuppressive microenvironment in human SCLC, identifying hybrid tumor cell states and their origins.
bioRxiv · Jan 19, 2022 · PreprintCancer Biology