Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma
T. Risom, D. R. Glass, C. C. Liu, B. Rivero-Gutierrez, A. Baranski, E. F. McCaffrey, N. F. Greenwald, A. C. Kagel, S. H. Strand, S. Varma, A. Kong, L. Keren, S. Srivastava, C. Zhu, Z. Khair, , M. Angelo
The paper analyzes tumor microenvironment changes from normal to invasive breast cancer using imaging and machine learning, finding coordinated shifts in stromal cell location and function.
bioRxiv · Jan 5, 2021Cancer Biology