Author

L. Keren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Approach:microscopy & imaging analysis· 2 Research Focus:spatial domain detection· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

M. Angelo· 3 shared A. Baranski· 2 shared E. F. McCaffrey· 2 shared N. F. Greenwald· 2 shared S. C. Bendall· 2 shared A. C. Kagel· 1 shared A. Delmastro· 1 shared A. J. C. Steyn· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

M. Angelo

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Author profile →

3 papers

Recent·Most cited

Multiplexed Imaging Analysis of the Tumor-Immune Microenvironment Reveals Predictors of Outcome in Triple-Negative Breast Cancer

A. N. Patwa, R. Yamashita, J. Long, M. Angelo, L. Keren, D. Rubin

The paper uses multiplexed ion-beam imaging to analyze the tumor-immune microenvironment in triple-negative breast cancer, identifying immunological predictors of patient outcomes.

bioRxiv · Jan 6, 2021Cancer Biology

Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma

T. Risom, D. R. Glass, C. C. Liu, B. Rivero-Gutierrez, A. Baranski, E. F. McCaffrey, N. F. Greenwald, A. C. Kagel, S. H. Strand, S. Varma, A. Kong, L. Keren, S. Srivastava, C. Zhu, Z. Khair, , M. Angelo

The paper analyzes tumor microenvironment changes from normal to invasive breast cancer using imaging and machine learning, finding coordinated shifts in stromal cell location and function.

bioRxiv · Jan 5, 2021Cancer Biology

Multiplexed imaging of human tuberculosis granulomas uncovers immunoregulatory features conserved across tissue and blood

E. F. McCaffrey, M. Donato, L. Keren, Z. Chen, M. Fitzpatrick, V. Jojic, A. Delmastro, N. F. Greenwald, A. Baranski, W. Graf, M. Bosse, P. K. Ramdial, E. Forgo, D. Van Valen, M. van de Rijn, , M. Angelo

This study uses multiplexed imaging and transcriptomics to identify immunosuppressive features in TB granulomas and blood, linking local and systemic immune responses.

bioRxiv · Jun 8, 2020 · PreprintImmunology