DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts
S. H. Strand, B. Rivero-Gutierrez, K. E. Houlahan, J. A. Seoane, L. M. King, T. Risom, L. A. Simpson, S. Vennam, A. Khan, L. Cisneros, T. Hardman, B. Harmon, F. Couch, K. Gallagher, M. Kilgore, , K Owzar
The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.
bioRxiv · Jun 16, 2021 · PreprintCancer Biology