Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro
D. Koch, A. L. Kho, A. Fukuzawa, A. Alexandrovich, A. Beavil, M. Pfuhl, M. Rees, M. Gautel
The paper investigates obscurin GEF domains, showing they are phosphorylated by MST-family kinases but lack detectable nucleotide exchange activity towards Rho GTPases in vitro.
bioRxiv · Oct 14, 2022 · PreprintBiochemistry