In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament
D. Tamborrini, Z. Wang, T. Wagner, S. Tacke, M. Stabrin, M. Grange, A. L. Kho, M. Rees, P. Bennett, M. Gautel, S. Raunser
This study reveals the 3D structure of relaxed cardiac sarcomeres using cryo-electron tomography, showing how thick filament components interact and function in muscle contraction.
bioRxiv · Apr 11, 2023 · PreprintBiochemistry