Author

A. Bernut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

A. R. Floto· 2 shared C. A. Loynes· 2 shared C. Langevin· 2 shared J.-L. Herrmann· 2 shared S. A. Renshaw· 2 shared S. Renshaw· 2 shared A. Ait Ali Said· 1 shared A. J. Cadby· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. R. Floto

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis

S. A. Leon-Icaza, M. Fretaud, S. Cornelie, C. Bureau, L. Yatime, A. R. Floto, S. Renshaw, J.-L. Herrmann, C. Langevin, C. Cougoule, A. Bernut

This study shows curcumin improves inflammation and tissue damage in cystic fibrosis by restoring NRF2 activity in zebrafish and patient-derived airway organoids.

bioRxiv · Mar 17, 2024Immunology

Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes

C. F. Muir, C. C. Reyes-Aldasoro, F. Ellett, T. Prajsnar, Y. X. Ho, A. Bernut, C. A. Loynes, S. Elworthy, K. A. Bowden, A. J. Cadby, L. Prince, J. S. King, A. M. Condliffe, S. Renshaw

The paper identifies pulsatile Class I PI3K activity on neutrophil phagosomes during bacterial infection, suggesting phagosomes reopen and reclose to release or restart digestion.

bioRxiv · Feb 29, 2024 · PreprintCell Biology

Roscovitine exacerbates Mycobacterium abscessus infection by reducing NADPH oxidase-dependent neutrophil trafficking

V. Le Moigne, D. Rodriguez Rincon, S. Glatigny, C. Dupont, C. Langevin, A. Ait Ali Said, S. A. Renshaw, A. R. Floto, J.-L. Herrmann, A. Bernut

This study shows Roscovitine reduces neutrophil trafficking by inhibiting NADPH oxidase, worsening Mycobacterium abscessus infection in CF models.

bioRxiv · Jul 30, 2021 · PreprintMicrobiology

Deletion of cftr leads to an excessive neutrophilic response and defective tissue repair in a zebrafish model of sterile inflammation

A. Bernut, C. A. Loynes, R. A. Floto, S. A. Renshaw

This study shows that CFTR deletion in zebrafish causes excessive neutrophilic inflammation and impaired tissue repair, which can be mitigated by Tanshinone IIA.

bioRxiv · Nov 14, 2019Immunology