Congenital T cell activation impairs transitional to follicular B cell maturation in humans
H. Allard-Chamard, K. Hillier, M. L. Ramseier, A. Bertocchi, N. Kaneko, K. Premo, T. Lam, G. Yuen, M. Karpel, V. S. Mahajan, C. Tsekeri, J. Vencic, R. Crotty, A. Sharda, S. Barmettler, , S. Pillai
Congenital T cell activation in CTLA4-deficient patients impairs transitional to follicular B cell maturation and can be rescued by CTLA4 replacement therapy in vivo.
bioRxiv · Feb 8, 2024Immunology