Sbh1/Sec61beta is a specific signal peptide receptor within the Sec61 channel
L. Yadhanapudi, M. Lommel, P. Bhadra, G. Barbieri, R. Singh, M. Jung, V. Helms, T. Eisgruber, F. Stengel, A. Boergel, K. Remans, K. Romisch
This study identifies Sbh1/Sec61β as a specific signal peptide receptor that recognizes and guides substrates into the Sec61 channel through its cytosolic IDR and conserved regions.
bioRxiv · Mar 12, 2024 · PreprintBiochemistry