Author

A. C. Benjamin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:spatial transcriptomics· 2 Research Focus:differential expression· 1

Frequent Co-Authors

S. E. Acton· 4 shared V. G. Martinez· 3 shared C. M. de Winde· 2 shared H. L. Horsnell· 2 shared S. Makris· 2 shared A. Arp· 1 shared A. Carver· 1 shared C. J. Tape· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

S. E. Acton

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Tissue homeostasis and adaptation to immune challenge resolved by fibroblast network mechanics

H. L. Horsnell, R. J. Tetley, H. de Belly, S. Makris, A. C. Benjamin, E. Paluch, Y. Mao, S. E. Acton

This study identifies how fibroblast network mechanics regulate tissue tension and adaptation to immune challenge in lymph nodes.

bioRxiv · May 27, 2021Immunology

Fibroblastic Reticular Cell Response to Dendritic Cells Requires Coordinated Activity of Podoplanin, CD44 and CD9

C. M. de Winde, S. Makris, L. Millward, J. Cantoral, A. C. Benjamin, V. G. Martinez, S. E. Acton

This study identifies that podoplanin, CD44, and CD9 are coregulated on fibroblastic reticular cells (FRCs) and work together to regulate FRC response to CLEC-2+ dendritic cells during lymph node expansion.

bioRxiv · Nov 20, 2020Cell Biology

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

C. M. de Winde, S. L. George, A. Arp, A. C. Benjamin, E. Crosas-Molist, Y. Hari-Gupta, A. Carver, V. Imperatore, V. G. Martinez, V. Sanz-Moreno, S. E. Acton

This study shows podoplanin promotes amoeboid invasion and dedifferentiation in melanoma, suggesting it as a biomarker and therapeutic target.

bioRxiv · Jul 23, 2020Cancer Biology

Conduit integrity is compromised during acute lymph node expansion

V. G. Martinez, V. Pankova, L. Krasny, T. Singh, I. J. White, A. C. Benjamin, S. Dertschnig, H. L. Horsnell, J. Kriston-Vizi, J. J. Burden, P. H. Huang, C. J. Tape, S. E. Acton

This study investigates how conduit integrity in lymph nodes changes during acute expansion, finding that while the structure is disrupted, FRC-FRC contacts remain intact and antigen flow becomes leaky.

bioRxiv · Mar 21, 2019Immunology