Pharmacology & ToxicologybioRxiv
Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel
C. Xiong, K. C. Chua, T. B. Stage…·D. L. Kroetz
This study uses human iPSC-derived sensory neurons to investigate the neurotoxic effects of paclitaxel and related drugs, finding dose- and time-dependent toxicity with varying IC50 values.