Direct activation of an innate immune system in bacteria by a viral capsid protein
T. Zhang, H. Tamman, K. Coppieters't Wallant, T. Kurata, M. LeRoux, S. Srikant, T. Brodiazhenko, A. Cepauskas, A. Talavera, C. Martens, G. C. Atkinson, V. Hauryliuk, A. Garcia-Pino, M. T. Laub
This study identifies a bacterial immune system that directly senses a viral capsid protein through a toxin-antitoxin system, revealing a PAMP-like mechanism for innate immunity in bacteria.
bioRxiv · May 30, 2022 · PreprintMicrobiology