Author

S. Jimmy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

V. Hauryliuk· 3 shared A. Garcia-Pino· 2 shared C. K. Saha· 2 shared G. C. Atkinson· 2 shared H. Strahl· 2 shared H. Takada· 2 shared S. R. A. Oliveira· 2 shared T. Kurata· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

V. Hauryliuk

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3 papers

Recent·Most cited

Panacea: a hyperpromiscuous antitoxin protein domain for the neutralisation of diverse toxin domains

T. Kurata, C. K. Saha, J. A. Buttress, T. Mets, T. Brodiazhenko, K. J. Turnbull, O. F. Awoyomi, S. R. A. Oliveira, S. Jimmy, K. Ernits, M. Delannoy, K. Persson, T. Tenson, H. Strahl, V. Hauryliuk, G. C. Atkinson

The paper identifies and validates a hyperpromiscuous antitoxin domain, Panacea, capable of neutralizing diverse toxin domains across microbial and bacteriophage TA systems.

bioRxiv · May 7, 2021Microbiology

Ribosome association primes the stringent factor Rel for recruitment of deacylated tRNA to ribosomal A-site

H. Takada, M. Roghanian, J. Caballero-Montes, K. Van Nerom, S. Jimmy, P. Kudrin, F. Trebini, R. Murayama, G. Akanuma, A. Garcia-Pino, V. Hauryliuk

The paper reveals how RelA/SpoT Homolog factor Rel in Bacillus subtilis detects amino acid starvation by interacting with deacylated tRNA on the ribosome, triggering (p)ppGpp synthesis.

bioRxiv · Jan 17, 2020 · PreprintBiochemistry

A widespread toxin-antitoxin system exploiting growth control via alarmone signalling

S. Jimmy, C. K. Saha, C. G. Stavropoulos, S. R. A. Oliveira, T. Kurata, A. Koh, A. Cepauskas, H. Takada, T. Tenson, H. Strahl, A. Garcia-Pino, V. Hauryliuk, G. C. Atkinson

The paper identifies toxin-antitoxin systems in bacteria using alarmone signalling, showing how SASs function as toxins and their antitoxins counteract them.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology