ImmunologybioRxivPreprint
PD-L1 Restrains the PD-1hiNrp1loTGFb+ Treg to block IL6+ Neutrophil tumor infiltration to Suppress Inflammation-driven Colorectal Cancer
K. Liu, D. B. Poschel, J. Klement…·H. Shi
This study shows PD-L1 suppresses inflammation-driven colorectal cancer by regulating Tregs, neutrophils, and gut microbiota through the PD-L1/L. murinus/PD-1hiNrp1loTGFβ+ Treg/IL6+ neutrophils pathway.
DOI 10.1101/2023.10.12.562132