Author

A. Dinis

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Anish VasaniD· 1 shared D. Camacho· 1 shared D. E. Ingber· 1 shared D. L. Kasper· 1 shared Donald E. IngberiD· 1 shared E. Gardner· 1 shared F. N. Grafton· 1 shared F. S. Gazzaniga· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Anish VasanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Target-agnostic discovery of Rett Syndrome therapeutics by coupling computational network analysis and CRISPR-enabled in vivo disease modeling

R. Novak, Tiffany Lin, S. Kaushal, Megan M. Sperry, Frédéric Vigneault, E. Gardner, Sahil Loomba, K. Shcherbina, Vishal Keshari, A. Dinis, Anish Vasan, V. Chandrasekhar, Takako Takeda, Jerrold R. Turner, Michael G. Levin, Donald E. Ingber

This paper identifies vorinostat as a potential repurposed therapy for Rett syndrome by combining computational network analysis with CRISPR-edited Xenopus models, showing efficacy across multiple organ systems.

bioRxiv · Mar 20, 2022 · PreprintNeuroscience

Harnessing Colon Chip technology to identify commensal bacteria that promote host tolerance to infection

F. S. Gazzaniga, D. Camacho, M. Wu, M. F. D. S. Palazzo, A. Dinis, F. N. Grafton, M. J. Cartwright, M. Super, D. L. Kasper, D. E. Ingber

The paper uses a microfluidic organ-on-a-chip model to identify commensal bacteria that enhance host tolerance to infection, finding Enterococcus faecium promotes tolerance.

bioRxiv · Dec 5, 2020Bioengineering